Anti-GATA3 antibody [SAA0103] {FITC} (STJA0028345)

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STJA0028345
£254.50 - £378.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Trans-Acting T-Cell-Specific Transcription Factor Gata-3 is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0103
Conjugation: FITC
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300
Purification: Purified
Concentration: 05 mg/mL
Storage Instruction: Store at 4°C for 12 months Protect from light Do not freeze
Gene Symbol: GATA3
Gene ID: 2625
Uniprot ID: GATA3_HUMAN
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
Protein Name Trans-Acting T-Cell-Specific Transcription Factor Gata-3
Gata-Binding Factor 3
Database Links Reactome: R-HSA-5689880
Reactome: R-HSA-6785807
Reactome: R-HSA-8939236
Reactome: R-HSA-9018519
Reactome: R-HSA-9830364
Reactome: R-HSA-983231
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Trans-Acting T-Cell-Specific Transcription Factor Gata-3 antibody
Anti-Gata-Binding Factor 3 antibody
Anti-GATA3 antibody

Information sourced from Uniprot.org