| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GATA2 |
| Gene ID: | 2624 |
| Uniprot ID: | GATA2_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GATA2 (NP_116027.2). |
| Immunogen Sequence: | MEVAPEQPRWMAHPAVLNAQ HPDSHHPGLAHNYMEPAQLL PPDEVDVFFNHLDSQGNPYY ANPAHARARVSYSPAHARLT GGQMCRPHLLHSPGLPWLDG GKAALSAAAAHHHNPWTVSP FSKTPLHPSAAGGPGGPLSV YPGAGGGSGGGSGSSVASLT PTAAHSGSHLFGFPPTPPKE VSPDPSTTGAASPASSSAGG SAARGEDKDGVKYQVSLTES MKMESGSPLRPGLATMGTQ |
| Tissue Specificity | Endothelial cells. |
| Function | Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'. |
| Protein Name | Endothelial Transcription Factor Gata-2Gata-Binding Protein 2 |
| Database Links | Reactome: R-HSA-8939236Reactome: R-HSA-9616222Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Endothelial Transcription Factor Gata-2 antibodyAnti-Gata-Binding Protein 2 antibodyAnti-GATA2 antibody |
Information sourced from Uniprot.org
