| Short Description : | Rabbit polyclonal GART (1-320) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GART |
| Gene ID: | 2618 |
| Uniprot ID: | PUR2_HUMAN |
| Immunogen Region: | 1-320 |
| Immunogen Sequence: | MAARVLIIGSGGREHTLAWK LAQSHHVKQVLVAPGNAGTA CSEKISNTAISISDHTALAQ FCKEKKIEFVVVGPEAPLAA GIVGNLRSAGVQCFGPTAEA AQLESSKRFAKEFMDRHGIP TAQWKAFTKPEEACSFILSA DFPALVVKASGLAAGKGVIV AKSKEEACKAVQEIMQEKAF GAAGETIVIEELLDGEEVSC LCFTDGKTVAPMPPAQDHKR LLEGDGGPNTGGMGAYCPA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human GART (NP_000810.1). |
| Function | Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway. |
| Protein Name | Trifunctional Purine Biosynthetic Protein Adenosine-3 Includes - Phosphoribosylamine--Glycine LigaseGlycinamide Ribonucleotide SynthetaseGarsPhosphoribosylglycinamide Synthetase - Phosphoribosylformylglycinamidine Cyclo-LigaseAir SynthaseAirsPhosphoribosyl-Aminoimidazole Synthetase - Phosphoribosylglycinamide Formyltransferase5'-Phosphoribosylglycinamide TransformylaseGar TransformylaseGart |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Trifunctional Purine Biosynthetic Protein Adenosine-3 Includes - Phosphoribosylamine--Glycine Ligase antibodyAnti-Glycinamide Ribonucleotide Synthetase antibodyAnti-Gars antibodyAnti-Phosphoribosylglycinamide Synthetase - Phosphoribosylformylglycinamidine Cyclo-Ligase antibodyAnti-Air Synthase antibodyAnti-Airs antibodyAnti-Phosphoribosyl-Aminoimidazole Synthetase - Phosphoribosylglycinamide Formyltransferase antibodyAnti-5'-Phosphoribosylglycinamide Transformylase antibodyAnti-Gar Transformylase antibodyAnti-Gart antibodyAnti-GART antibodyAnti-PGFT antibodyAnti-PRGS antibody |
Information sourced from Uniprot.org
