| Short Description : | Rabbit polyclonal anti-Neutral alpha-glucosidase AB (242-291 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GANAB |
| Gene ID: | 23193 |
| Uniprot ID: | GANAB_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GANAB at the amino acid range 242-291 |
| Immunogen Region: | 242-291 aa |
| Specificity: | Glucosidase II Alpha Polyclonal Antibody detects endogenous levels of Glucosidase II Alpha protein. |
| Function | Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia. |
| Protein Name | Neutral Alpha-Glucosidase AbAlpha-Glucosidase 2Glucosidase Ii Subunit Alpha |
| Database Links | Reactome: R-HSA-532668Reactome: R-HSA-901042Reactome: R-HSA-9683686Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Neutral Alpha-Glucosidase Ab antibodyAnti-Alpha-Glucosidase 2 antibodyAnti-Glucosidase Ii Subunit Alpha antibodyAnti-GANAB antibodyAnti-G2AN antibodyAnti-KIAA0088 antibody |
Information sourced from Uniprot.org
