| Post Translational Modifications | Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome. |
| Function | Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Tubulin Gamma-1 ChainGamma-1-TubulinGamma-Tubulin Complex Component 1Gcp-1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleLocalizes To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Tubulin Gamma-1 Chain antibodyAnti-Gamma-1-Tubulin antibodyAnti-Gamma-Tubulin Complex Component 1 antibodyAnti-Gcp-1 antibodyAnti-TUBG1 antibodyAnti-TUBG antibody |
Information sourced from Uniprot.org
