| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000IHC-P:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GADD45A |
| Gene ID: |
1647 |
| Uniprot ID: |
GA45A_HUMAN |
| Immunogen Region: |
60-160 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 60-160 of human GADD45A (NP_001915.1). |
| Immunogen Sequence: |
AADEDDDRDVALQIHFTLIQ AFCCENDINILRVSNPGRLA ELLLLETDAGPAASEGAEQP PDLHCVLVTNPHSSQWKDPA LSQLICFCRESRYMDQWVPV I |
| Function | In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes.stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. |
| Protein Name | Growth Arrest And Dna Damage-Inducible Protein Gadd45 AlphaDna Damage-Inducible Transcript 1 ProteinDdit-1 |
| Database Links | Reactome: R-HSA-6804114Reactome: R-HSA-9617828 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Growth Arrest And Dna Damage-Inducible Protein Gadd45 Alpha antibodyAnti-Dna Damage-Inducible Transcript 1 Protein antibodyAnti-Ddit-1 antibodyAnti-GADD45A antibodyAnti-DDIT1 antibodyAnti-GADD45 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
