Anti-GAD1 antibody (1-200) (STJ23736)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GAD1 (1-200) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAD1 |
| Gene ID | 2571 |
| Uniprot ID | DCE1_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | AGYLFQPDKQYDVSYDTGDK AIQCGRHVDIFKFWLMWKAK GTVGFENQINKCLELAEYLY AKIKNREEFEMVFNGEPEHT NVCFWYIPQSLRGVPDSPQR REKLHKVAPKIKALMMESGT TMVGYQPQGDKANFFRMVIS NPAATQSDIDFLIEEIERLG QDL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 432-594 of human GAD67/GAD1 (NP_000808.2). |
Additional Info
| Tissue Specificity | Isoform 1: Expressed in brain. Isoform 3: Expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. |
| Function | Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. Isoform 3: Enzymatically inactive as glutamate decarboxylase. |
| Protein Name | Glutamate Decarboxylase 167 Kda Glutamic Acid DecarboxylaseGad-67Glutamate Decarboxylase 67 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 1 antibodyAnti-67 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-67 antibodyAnti-Glutamate Decarboxylase 67 Kda Isoform antibodyAnti-GAD1 antibodyAnti-GAD antibodyAnti-GAD67 antibody |
Information sourced from Uniprot.org