| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
GABPB1 |
| Gene ID: |
2553 |
| Uniprot ID: |
GABP1_HUMAN |
| Immunogen Region: |
290-395 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 290-395 of human GABPB1 (NP_005245.2). |
| Immunogen Sequence: |
TSGIGQPIIVTMPDGQQVLT VPATDIAEETVISEEPPAKR QCIEIIENRVESAEIEEREA LQKQLDEANREAQKYRQQLL KKEQEAEAYRQKLEAMTRLQ TNKEAV |
| Post Translational Modifications | Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity. |
| Function | Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a master regulator of nuclear-encoded mitochondrial genes. (Microbial infection) Necessary for the expression of the Adenovirus E4 gene. |
| Protein Name | Ga-Binding Protein Subunit Beta-1Gabp Subunit Beta-1Gabpb-1Gabp Subunit Beta-2Gabpb-2Nuclear Respiratory Factor 2Transcription Factor E4tf1-47Transcription Factor E4tf1-53 |
| Database Links | Reactome: R-HSA-2151201 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ga-Binding Protein Subunit Beta-1 antibodyAnti-Gabp Subunit Beta-1 antibodyAnti-Gabpb-1 antibodyAnti-Gabp Subunit Beta-2 antibodyAnti-Gabpb-2 antibodyAnti-Nuclear Respiratory Factor 2 antibodyAnti-Transcription Factor E4tf1-47 antibodyAnti-Transcription Factor E4tf1-53 antibodyAnti-GABPB1 antibodyAnti-E4TF1B antibodyAnti-GABPB antibodyAnti-GABPB2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
