| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GABPB1 |
| Gene ID: | 2553 |
| Uniprot ID: | GABP1_HUMAN |
| Immunogen Region: | 231-395 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-395 of human GABPB1 (NP_005245.2). |
| Immunogen Sequence: | AEASAPLSNSSETPVVATEE VVTAESVDGAIQQVVSSGGQ QVITIVTDGIQLGNLHSIPT SGIGQPIIVTMPDGQQVLTV PATDIAEETVISEEPPAKRQ CIEIIENRVESAEIEEREAL QKQLDEANREAQKYRQQLLK KEQEAEAYRQKLEAMTRLQT NKEAV |
| Post Translational Modifications | Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity. |
| Function | Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a master regulator of nuclear-encoded mitochondrial genes. (Microbial infection) Necessary for the expression of the Adenovirus E4 gene. |
| Protein Name | Ga-Binding Protein Subunit Beta-1Gabp Subunit Beta-1Gabpb-1Gabp Subunit Beta-2Gabpb-2Nuclear Respiratory Factor 2Transcription Factor E4tf1-47Transcription Factor E4tf1-53 |
| Database Links | Reactome: R-HSA-2151201 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ga-Binding Protein Subunit Beta-1 antibodyAnti-Gabp Subunit Beta-1 antibodyAnti-Gabpb-1 antibodyAnti-Gabp Subunit Beta-2 antibodyAnti-Gabpb-2 antibodyAnti-Nuclear Respiratory Factor 2 antibodyAnti-Transcription Factor E4tf1-47 antibodyAnti-Transcription Factor E4tf1-53 antibodyAnti-GABPB1 antibodyAnti-E4TF1B antibodyAnti-GABPB antibodyAnti-GABPB2 antibody |
Information sourced from Uniprot.org