• Western blot analysis of MCF7, using GABPB1 antibody (STJ28989) at 1:600 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-GABPB1 antibody (231-395) (STJ28989)

SKU:
STJ28989

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GABPB1 (231-395) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GABPB1
Gene ID: 2553
Uniprot ID: GABP1_HUMAN
Immunogen Region: 231-395
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 231-395 of human GABPB1 (NP_005245.2).
Immunogen Sequence: AEASAPLSNSSETPVVATEE VVTAESVDGAIQQVVSSGGQ QVITIVTDGIQLGNLHSIPT SGIGQPIIVTMPDGQQVLTV PATDIAEETVISEEPPAKRQ CIEIIENRVESAEIEEREAL QKQLDEANREAQKYRQQLLK KEQEAEAYRQKLEAMTRLQT NKEAV
Post Translational Modifications Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.
Function Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. (Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
Protein Name Ga-Binding Protein Subunit Beta-1
Gabp Subunit Beta-1
Gabpb-1
Gabp Subunit Beta-2
Gabpb-2
Nuclear Respiratory Factor 2
Transcription Factor E4tf1-47
Transcription Factor E4tf1-53
Database Links Reactome: R-HSA-2151201
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ga-Binding Protein Subunit Beta-1 antibody
Anti-Gabp Subunit Beta-1 antibody
Anti-Gabpb-1 antibody
Anti-Gabp Subunit Beta-2 antibody
Anti-Gabpb-2 antibody
Anti-Nuclear Respiratory Factor 2 antibody
Anti-Transcription Factor E4tf1-47 antibody
Anti-Transcription Factor E4tf1-53 antibody
Anti-GABPB1 antibody
Anti-E4TF1B antibody
Anti-GABPB antibody
Anti-GABPB2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance