Anti-GAB1 antibody (611-643 aa) (STJ93177)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GAB1 at the amino acid range 611-643
General Information
| Short Description | Rabbit polyclonal anti-GRB2-associated-binding protein 1 (611-643 aa) for use in WB, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAB1 |
| Gene ID | 2549 |
| Uniprot ID | GAB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GAB1 at the amino acid range 611-643 |
| Immunogen Region | 611-643 aa |
| Specificity | Gab 1 Polyclonal Antibody detects endogenous levels of Gab 1 protein. |
Additional Info
| Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. |
| Protein Name | Grb2-Associated-Binding Protein 1Grb2-Associated Binder 1Growth Factor Receptor Bound Protein 2-Associated Protein 1 |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1236382Reactome: R-HSA-1257604Reactome: R-HSA-180292Reactome: R-HSA-1963642Reactome: R-HSA-2219530Reactome: R-HSA-5637810Reactome: R-HSA-5654689Reactome: R-HSA-5654695Reactome: R-HSA-5654710Reactome: R-HSA-5654720Reactome: R-HSA-5655253Reactome: R-HSA-5655291Reactome: R-HSA-5655302Reactome: R-HSA-5655332Reactome: R-HSA-6811558Reactome: R-HSA-8851907Reactome: R-HSA-8853659Reactome: R-HSA-8865999Reactome: R-HSA-8875555Reactome: R-HSA-8875656Reactome: R-HSA-9027276Reactome: R-HSA-9028335Reactome: R-HSA-9664565Reactome: R-HSA-9665348 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Grb2-Associated-Binding Protein 1 antibodyAnti-Grb2-Associated Binder 1 antibodyAnti-Growth Factor Receptor Bound Protein 2-Associated Protein 1 antibodyAnti-GAB1 antibody |
Information sourced from Uniprot.org