Host: | Mouse |
Applications: | WB/IHC/IF/FC/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Glucose-6-phosphate 1-dehydrogenase is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | 2H7 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000FC 1:200-1:400ELISA 1:10000IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | G6PD |
Gene ID: | 2539 |
Uniprot ID: | G6PD_HUMAN |
Specificity: | G6PD Monoclonal Antibody detects endogenous levels of G6PD protein. |
Immunogen: | Purified recombinant fragment of human G6PD expressed in E. Coli. |
Post Translational Modifications | Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity. |
Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. |
Protein Name | Glucose-6-Phosphate 1-DehydrogenaseG6pd |
Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-71336Reactome: R-HSA-9818028 |
Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Glucose-6-Phosphate 1-Dehydrogenase antibodyAnti-G6pd antibodyAnti-G6PD antibody |
Information sourced from Uniprot.org