| Host: | Mouse | 
| Applications: | WB/IHC/IF/FC/ELISA | 
| Reactivity: | Human | 
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. | 
| Short Description : | Mouse monoclonal antibody anti-Glucose-6-phosphate 1-dehydrogenase is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications. | 
| Clonality : | Monoclonal | 
| Clone ID : | 2H7 | 
| Conjugation: | Unconjugated | 
| Isotype: | IgG1 | 
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. | 
| Purification: | Affinity purification | 
| Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000FC 1:200-1:400ELISA 1:10000IF 1:50-200 | 
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. | 
| Gene Symbol: | G6PD | 
| Gene ID: | 2539 | 
| Uniprot ID: | G6PD_HUMAN | 
| Specificity: | G6PD Monoclonal Antibody detects endogenous levels of G6PD protein. | 
| Immunogen: | Purified recombinant fragment of human G6PD expressed in E. Coli. | 
| Post Translational Modifications | Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity. | 
| Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. | 
| Protein Name | Glucose-6-Phosphate 1-DehydrogenaseG6pd | 
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-71336Reactome: R-HSA-9818028 | 
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein | 
| Alternative Antibody Names | Anti-Glucose-6-Phosphate 1-Dehydrogenase antibodyAnti-G6pd antibodyAnti-G6PD antibody | 
Information sourced from Uniprot.org
                    
                    
                    
                    
                       
                    
