Anti-G0S2 antibody (1-100) (STJ112011)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal G0S2 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | G0S2 |
| Gene ID | 50486 |
| Uniprot ID | G0S2_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | METVQELIPLAKEMMAQKRK GKMVKLYVLGSVLALFGVVL GLMETVCSPFTAARRLRDQE AAVAELQAALERQALQKQAL QEKGKQQDTVLGGRALSNRQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human G0S2 (NP_056529.1). |
Additional Info
| Tissue Specificity | Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver. |
| Function | Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. |
| Protein Name | G0/G1 Switch Protein 2G0/G1 Switch Regulatory Protein 2Putative Lymphocyte G0/G1 Switch Gene |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-G0/G1 Switch Protein 2 antibodyAnti-G0/G1 Switch Regulatory Protein 2 antibodyAnti-Putative Lymphocyte G0/G1 Switch Gene antibodyAnti-G0S2 antibody |
Information sourced from Uniprot.org