| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | G0S2 |
| Gene ID: | 50486 |
| Uniprot ID: | G0S2_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human G0S2 (NP_056529.1). |
| Immunogen Sequence: | METVQELIPLAKEMMAQKRK GKMVKLYVLGSVLALFGVVL GLMETVCSPFTAARRLRDQE AAVAELQAALERQALQKQAL QEKGKQQDTVLGGRALSNRQ |
| Tissue Specificity | Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver. |
| Function | Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. |
| Protein Name | G0/G1 Switch Protein 2G0/G1 Switch Regulatory Protein 2Putative Lymphocyte G0/G1 Switch Gene |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-G0/G1 Switch Protein 2 antibodyAnti-G0/G1 Switch Regulatory Protein 2 antibodyAnti-Putative Lymphocyte G0/G1 Switch Gene antibodyAnti-G0S2 antibody |
Information sourced from Uniprot.org