| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-G-CSF receptor (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000. WB: Preliminary experiments in Human Placenta, Bone marrow and peripheral lymphocytes lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would a |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CSF3R |
| Gene ID: | 1441 |
| Uniprot ID: | CSF3R_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000751.1; NP_724781.1; NP_758519.1 |
| Specificity: | This antibody is expected to recognize all reported isoforms (NP_000751.1; NP_724781.1; NP_758519.1). |
| Immunogen Sequence: | TQGDSILDCVPKDGQ |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
| Protein Name | Granulocyte Colony-Stimulating Factor Receptor G-Csf Receptor G-Csf-R Cd Antigen Cd114 |
| Database Links | Reactome: R-HSA-449836 Reactome: R-HSA-9616222 Reactome: R-HSA-9674555 Reactome: R-HSA-9705462 |
| Cellular Localisation | Isoform 2: Secreted Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Granulocyte Colony-Stimulating Factor Receptor antibody Anti-G-Csf Receptor antibody Anti-G-Csf-R antibody Anti-Cd Antigen Cd114 antibody Anti-CSF3R antibody Anti-GCSFR antibody |
Information sourced from Uniprot.org