| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : |
Mouse monoclonal antibody anti-Frizzled-5 is suitable for use in ELISA research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA1670 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Function | Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling. In neurons, activation by WNT7A promotes formation of synapses. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization. Plays a role in ocular development. |
| Protein Name | Frizzled-5Fz-5Hfz5Fze5 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-4086398Reactome: R-HSA-4608870Reactome: R-HSA-4641262Reactome: R-HSA-4641263Reactome: R-HSA-5140745Reactome: R-HSA-5340588 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneSynapsePerikaryonCell ProjectionDendriteAxonLocalized At The Plasma Membrane And Also Found At The Golgi Apparatus |
| Alternative Antibody Names | Anti-Frizzled-5 antibodyAnti-Fz-5 antibodyAnti-Hfz5 antibodyAnti-Fze5 antibodyAnti-FZD5 antibodyAnti-C2orf31 antibody |
Information sourced from Uniprot.org
