| Post Translational Modifications | N-glycosylated with complex-type N-glycans. The glycan alpha-D-Man-(1->3)-beta-D-Man-(1->4)-GlcNAc-(1->4)-GlcNAc is attached at Asn-153. |
| Function | Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc-) glycan attached to glycolipids and N- or O-linked glycoproteins. Fucosylates distal type 2 LacNAc and its fucosylated (H-type 2 LacNAc) and sialylated (sialyl-type 2 LacNAc) derivatives to form Lewis x (Lex) (CD15) and Lewis y (Ley) antigenic epitopes involved in cell adhesion and differentiation. Generates Lex epitopes in the brain, presumably playing a role in the maintenance of neuronal stemness and neurite outgrowth in progenitor neural cells. Fucosylates the internal type 2 LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Can also modify milk oligosaccharides, in particular type 2 tetrasaccharide LNnT. |
| Protein Name | 4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase 9Fucosyltransferase 9Fucosyltransferase IxFuc-TixFuct-IxGalactoside 3-L-Fucosyltransferase |
| Database Links | Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase 9 antibodyAnti-Fucosyltransferase 9 antibodyAnti-Fucosyltransferase Ix antibodyAnti-Fuc-Tix antibodyAnti-Fuct-Ix antibodyAnti-Galactoside 3-L-Fucosyltransferase antibodyAnti-FUT9 antibody |
Information sourced from Uniprot.org
