| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Alpha-1, 3-fucosyltransferase 10 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FUT10 |
| Gene ID: |
84750 |
| Uniprot ID: |
FUT10_HUMAN |
| Specificity: |
This antibody detects endogenous levels of FUT10 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human FUT10 |
| Function | Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation. Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development. Isoform 1: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit. Isoform 4: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit. Isoform 5: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit. |
| Protein Name | Alpha-(1 -3-Fucosyltransferase 10Fucosyltransferase XFuc-TxFuct-XGalactoside 3-L-Fucosyltransferase 10Fucosyltransferase 10 |
| Database Links | Reactome: R-HSA-9037629 |
| Cellular Localisation | Isoform 1: Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneIsoform 4: Golgi ApparatusLysosomeIsoform 5: Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Alpha-(1 -3-Fucosyltransferase 10 antibodyAnti-Fucosyltransferase X antibodyAnti-Fuc-Tx antibodyAnti-Fuct-X antibodyAnti-Galactoside 3-L-Fucosyltransferase 10 antibodyAnti-Fucosyltransferase 10 antibodyAnti-FUT10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
