Host: | Goat |
Applications: | WB/IHC-F/IHC-P/IF |
Reactivity: | Human/Rat/Mouse/Monkey/Canine |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-Formimidoyltransferase cyclodeaminase (50aa N-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
Purification: | This antibody is epitope-affinity purified from goat antiserum. |
Concentration: | 3 mg/mL |
Dilution Range: | WB 1:500-1:2000IF 1:25-1:250IHC-F 1:250-1:1000IHC-P 1:250-1:1000 |
Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
Gene Symbol: | FTCD |
Gene ID: | 10841 |
Uniprot ID: | FTCD_HUMAN |
Immunogen Region: | 50aa N-Term |
Accession Number: | ENSG00000160282 |
Specificity: | Detects a band of 55-60 kDa by Western blot in the following canine, human, monkey, mouse, rat whole cell lysates. |
Immunogen: | Purified recombinant peptide derived from within residues 50 aa to the N-terminus of human FTCD produced in E. coli. |
Immunogen Sequence: | MSQLVECVPNFSEGKNQEVI DAISGAITQTPGCVLLDVDA GPSTNRTVYTFVGPP |
Function | Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi. |
Protein Name | Formimidoyltransferase-CyclodeaminaseFormiminotransferase-CyclodeaminaseFtcdLchc1 Includes - Glutamate FormimidoyltransferaseGlutamate FormiminotransferaseGlutamate Formyltransferase - Formimidoyltetrahydrofolate CyclodeaminaseFormiminotetrahydrofolate Cyclodeaminase |
Database Links | Reactome: R-HSA-70921 |
Cellular Localisation | CytoplasmCytosolGolgi ApparatusCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleMore Abundantly Located Around The Mother Centriole |
Alternative Antibody Names | Anti-Formimidoyltransferase-Cyclodeaminase antibodyAnti-Formiminotransferase-Cyclodeaminase antibodyAnti-Ftcd antibodyAnti-Lchc1 Includes - Glutamate Formimidoyltransferase antibodyAnti-Glutamate Formiminotransferase antibodyAnti-Glutamate Formyltransferase - Formimidoyltetrahydrofolate Cyclodeaminase antibodyAnti-Formiminotetrahydrofolate Cyclodeaminase antibodyAnti-FTCD antibody |
Information sourced from Uniprot.org