Tissue Specificity | Overexpressed in synovial tissues from rheumatoid arthritis. |
Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. |
Protein Name | Follistatin-Related Protein 1Follistatin-Like Protein 1 |
Database Links | Reactome: R-HSA-201451Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Follistatin-Related Protein 1 antibodyAnti-Follistatin-Like Protein 1 antibodyAnti-FSTL1 antibodyAnti-FRP antibody |
Information sourced from Uniprot.org