Anti-FSH antibody (Full length) [ZR246] (STJ180570)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant full-length hFSH beta sub-unit
General Information
| Short Description | Rabbit monoclonal FSH (Full length) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR246 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | FSHB |
| Gene ID | 2488 |
| Uniprot ID | FSHB_HUMAN |
| Immunogen | Recombinant full-length hFSH beta sub-unit |
| Immunogen Region | Full length |
| Specificity | Positive Control: Pituitary |
Additional Info
| Function | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. |
| Protein Name | Follitropin Subunit BetaFollicle-Stimulating Hormone Beta SubunitFsh-BFsh-BetaFollitropin Beta Chain |
| Database Links | Reactome: R-HSA-209822Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | SecretedEfficient Secretion Requires Dimerization With Cga |
| Alternative Antibody Names | Anti-Follitropin Subunit Beta antibodyAnti-Follicle-Stimulating Hormone Beta Subunit antibodyAnti-Fsh-B antibodyAnti-Fsh-Beta antibodyAnti-Follitropin Beta Chain antibodyAnti-FSHB antibody |
Information sourced from Uniprot.org