Anti-FRS3 antibody (191-240 aa) (STJ93158)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human FRS3 at the amino acid range 191-240
General Information
| Short Description | Rabbit polyclonal anti-Fibroblast growth factor receptor substrate 3 (191-240 aa) for use in WB and ELISA in Human and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FRS3 |
| Gene ID | 10817 |
| Uniprot ID | FRS3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human FRS3 at the amino acid range 191-240 |
| Immunogen Region | 191-240 aa |
| Specificity | FRS3 Polyclonal Antibody detects endogenous levels of FRS3 protein. |
Additional Info
| Function | Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. |
| Protein Name | Fibroblast Growth Factor Receptor Substrate 3Fgfr Substrate 3Fgfr-Signaling Adaptor Snt2Suc1-Associated Neurotrophic Factor Target 2Snt-2 |
| Database Links | Reactome: R-HSA-5654693Reactome: R-HSA-5654700Reactome: R-HSA-5654706Reactome: R-HSA-5654712Reactome: R-HSA-5673001Reactome: R-HSA-9028731Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-9725370 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor Receptor Substrate 3 antibodyAnti-Fgfr Substrate 3 antibodyAnti-Fgfr-Signaling Adaptor Snt2 antibodyAnti-Suc1-Associated Neurotrophic Factor Target 2 antibodyAnti-Snt-2 antibodyAnti-FRS3 antibody |
Information sourced from Uniprot.org