• Western blot analysis of lysates from Jurkat cells, using FRK Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HUVEC cells, using FRK Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FRK Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Rak Polyclonal Antibody

Anti-FRK antibody (71-120 aa) (STJ95361)

SKU:
STJ95361

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tyrosine-protein kinase FRK (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FRK
Gene ID: 2444
Uniprot ID: FRK_HUMAN
Immunogen Region: 71-120 aa
Specificity: Rak Polyclonal Antibody detects endogenous levels of Rak protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human FRK at the amino acid range 71-120
Function Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Protein Name Tyrosine-Protein Kinase Frk
Fyn-Related Kinase
Nuclear Tyrosine Protein Kinase Rak
Protein-Tyrosine Kinase 5
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8948751
Cellular Localisation Cytoplasm
Nucleus
Predominantly Found In The Nucleus
With A Small Fraction Found In The Cell Periphery
Alternative Antibody Names Anti-Tyrosine-Protein Kinase Frk antibody
Anti-Fyn-Related Kinase antibody
Anti-Nuclear Tyrosine Protein Kinase Rak antibody
Anti-Protein-Tyrosine Kinase 5 antibody
Anti-FRK antibody
Anti-PTK5 antibody
Anti-RAK antibody

Information sourced from Uniprot.org

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