| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Protein FRG1 (184-234 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FRG1 |
| Gene ID: | 2483 |
| Uniprot ID: | FRG1_HUMAN |
| Immunogen Region: | 184-234 aa |
| Specificity: | This antibody detects endogenous levels of human FRG1 |
| Immunogen: | Synthesized peptide derived from the human FRG1 at the amino acid range 184-234 |
| Function | Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B. |
| Protein Name | Protein Frg1Fshd Region Gene 1 Protein |
| Database Links | |
| Cellular Localisation | NucleusCajal BodyNucleolusCytoplasmMyofibrilSarcomereZ LineLocalization Changes During Myogenesis From Mainly Cytoplasmic In Undifferentiated MyoblastsTo Strongly Nucleolar In Early Myotubes And Back To Cytoplasmic 5 Days Post-DifferentiationLocalized At The Z-Line In The Sarcomere Of Matured Myotubes 8 Days Post-Differentiation |
| Alternative Antibody Names | Anti-Protein Frg1 antibodyAnti-Fshd Region Gene 1 Protein antibodyAnti-FRG1 antibody |
Information sourced from Uniprot.org
