Anti-FOXP2 antibody (590-715) (STJ27644)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FOXP2 (590-715) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FOXP2 |
| Gene ID | 93986 |
| Uniprot ID | FOXP2_HUMAN |
| Immunogen Region | 590-715 |
| Immunogen Sequence | GSPTLVKNIPTSLGYGAALN ASLQAALAESSLPLLSNPGL INNASSGLLQAVHEDLNGSL DHIDSNGNSSPGCSPQPHIH SIHVKEEPVIAEDEDCPMSL VTTANHSPELEDDREIEEEP LSEDLE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 590-715 of human FOXP2 (NP_055306.1). |
Additional Info
| Tissue Specificity | Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. |
| Function | Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Protein Name | Forkhead Box Protein P2Cag Repeat Protein 44Trinucleotide Repeat-Containing Gene 10 Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein P2 antibodyAnti-Cag Repeat Protein 44 antibodyAnti-Trinucleotide Repeat-Containing Gene 10 Protein antibodyAnti-FOXP2 antibodyAnti-CAGH44 antibodyAnti-TNRC10 antibody |
Information sourced from Uniprot.org