| Tissue Specificity | Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas. |
| Post Translational Modifications | Phosphorylated. |
| Function | Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. |
| Protein Name | Forkhead Box Protein E1Forkhead Box Protein E2Forkhead-Related Protein Fkhl15Hfkh4Hnf-3/Fork Head-Like Protein 5Hfkl5Thyroid Transcription Factor 2Ttf-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein E1 antibodyAnti-Forkhead Box Protein E2 antibodyAnti-Forkhead-Related Protein Fkhl15 antibodyAnti-Hfkh4 antibodyAnti-Hnf-3/Fork Head-Like Protein 5 antibodyAnti-Hfkl5 antibodyAnti-Thyroid Transcription Factor 2 antibodyAnti-Ttf-2 antibodyAnti-FOXE1 antibodyAnti-FKHL15 antibodyAnti-FOXE2 antibodyAnti-TITF2 antibodyAnti-TTF2 antibody |
Information sourced from Uniprot.org
