• Immunohistochemical analysis of paraffin-embedded human colon cancer. 1, Tris-EDTA, pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200 (4°C overnight. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-FOLH1 antibody [1F12] (STJ196670)

SKU:
STJ196670

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Glutamate carboxypeptidase 2 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 1F12
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FOLH1
Gene ID: 2346
Uniprot ID: FOLH1_HUMAN
Specificity: This antibody detects endogenous levels of PSMA at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the human PSMA
Post Translational Modifications The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked.
Function Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Protein Name Glutamate Carboxypeptidase 2
Cell Growth-Inhibiting Gene 27 Protein
Folate Hydrolase 1
Folylpoly-Gamma-Glutamate Carboxypeptidase
Fgcp
Glutamate Carboxypeptidase Ii
Gcpii
Membrane Glutamate Carboxypeptidase
Mgcp
N-Acetylated-Alpha-Linked Acidic Dipeptidase I
Naaladase I
Prostate-Specific Membrane Antigen
Psm
Psma
Pteroylpoly-Gamma-Glutamate Carboxypeptidase
Database Links Reactome: R-HSA-8963693
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform Psma': Cytoplasm
Alternative Antibody Names Anti-Glutamate Carboxypeptidase 2 antibody
Anti-Cell Growth-Inhibiting Gene 27 Protein antibody
Anti-Folate Hydrolase 1 antibody
Anti-Folylpoly-Gamma-Glutamate Carboxypeptidase antibody
Anti-Fgcp antibody
Anti-Glutamate Carboxypeptidase Ii antibody
Anti-Gcpii antibody
Anti-Membrane Glutamate Carboxypeptidase antibody
Anti-Mgcp antibody
Anti-N-Acetylated-Alpha-Linked Acidic Dipeptidase I antibody
Anti-Naaladase I antibody
Anti-Prostate-Specific Membrane Antigen antibody
Anti-Psm antibody
Anti-Psma antibody
Anti-Pteroylpoly-Gamma-Glutamate Carboxypeptidase antibody
Anti-FOLH1 antibody
Anti-FOLH antibody
Anti-NAALAD1 antibody
Anti-PSM antibody
Anti-PSMA antibody
Anti-GIG27 antibody

Information sourced from Uniprot.org

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