Immunohistochemistry of mouse tissue with Anti-FNDC5 primary antibody (STJ501503) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-FNDC5 antibody (STJ501503)

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STJ501503-100
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-FNDC5 is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.59 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Fndc5
Gene ID: 384061
Uniprot ID: FNDC5_MOUSE
Immunogen: Synthetic peptide corresponding to unique amino acid sequences on human FNDC5 protein.
Tissue Specificity In adult, it is highly expressed in skeletal muscle, heart and brain.
Post Translational Modifications The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Protein Name Fibronectin Type Iii Domain-Containing Protein 5
Fibronectin Type Iii Repeat-Containing Protein 2
Peroxisomal Protein
Pep Cleaved Into - Irisin
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Peroxisome Membrane
Secreted
Imported In Peroxisomes Through The Pex5 Receptor Pathway
Irisin: Secreted
Detected In The Blood Of Individuals Subjected To Endurance Exercise
Alternative Antibody Names Anti-Fibronectin Type Iii Domain-Containing Protein 5 antibody
Anti-Fibronectin Type Iii Repeat-Containing Protein 2 antibody
Anti-Peroxisomal Protein antibody
Anti-Pep Cleaved Into - Irisin antibody
Anti-Fndc5 antibody
Anti-Frcp2 antibody
Anti-Pep antibody

Information sourced from Uniprot.org

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