Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Flavin-containing monooxygenase 3 (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FMO3 |
Gene ID: |
2328 |
Uniprot ID: |
FMO3_HUMAN |
Immunogen Region: |
101-150 aa |
Specificity: |
FMO3 Polyclonal Antibody detects endogenous levels of FMO3 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human FMO3 at the amino acid range 101-150 |
Function | Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation. |
Protein Name | Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3Dimethylaniline Oxidase 3Fmo IiFmo Form 2Hepatic Flavin-Containing Monooxygenase 3Fmo 3Trimethylamine Monooxygenase |
Database Links | Reactome: R-HSA-217271Reactome: R-HSA-5579019 |
Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 3 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibodyAnti-Dimethylaniline Oxidase 3 antibodyAnti-Fmo Ii antibodyAnti-Fmo Form 2 antibodyAnti-Hepatic Flavin-Containing Monooxygenase 3 antibodyAnti-Fmo 3 antibodyAnti-Trimethylamine Monooxygenase antibodyAnti-FMO3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance