| Function | Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation. |
| Protein Name | Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3Dimethylaniline Oxidase 3Fmo IiFmo Form 2Hepatic Flavin-Containing Monooxygenase 3Fmo 3Trimethylamine Monooxygenase |
| Database Links | Reactome: R-HSA-217271Reactome: R-HSA-5579019 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 3 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibodyAnti-Dimethylaniline Oxidase 3 antibodyAnti-Fmo Ii antibodyAnti-Fmo Form 2 antibodyAnti-Hepatic Flavin-Containing Monooxygenase 3 antibodyAnti-Fmo 3 antibodyAnti-Trimethylamine Monooxygenase antibodyAnti-FMO3 antibody |
Information sourced from Uniprot.org
