Anti-FMNL3 antibody (96-146 aa) (STJ194774)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human FMNL3 at the amino acid range 96-146
General Information
| Short Description | Rabbit polyclonal anti-Formin-like protein 3 (96-146 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FMNL3 |
| Gene ID | 91010 |
| Uniprot ID | FMNL3_HUMAN |
| Immunogen | Synthesized peptide derived from the human FMNL3 at the amino acid range 96-146 |
| Immunogen Region | 96-146 aa |
| Specificity | This antibody detects endogenous levels of FMNL3 at Human/Mouse |
Additional Info
| Function | Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis. In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement. |
| Protein Name | Formin-Like Protein 3Formin Homology 2 Domain-Containing Protein 3Ww Domain-Binding Protein 3Wbp-3 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013409 |
| Cellular Localisation | CytoplasmCell MembraneLipid-AnchorEnriched In Lamellipodia |
| Alternative Antibody Names | Anti-Formin-Like Protein 3 antibodyAnti-Formin Homology 2 Domain-Containing Protein 3 antibodyAnti-Ww Domain-Binding Protein 3 antibodyAnti-Wbp-3 antibodyAnti-FMNL3 antibodyAnti-FHOD3 antibodyAnti-FRL2 antibodyAnti-KIAA2014 antibodyAnti-WBP3 antibody |
Information sourced from Uniprot.org