| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | FGL1 |
| Gene ID: | 2267 |
| Uniprot ID: | FGL1_HUMAN |
| Immunogen Region: | 1-312 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human FGL1 (NP_004458.3). |
| Immunogen Sequence: | MAKVFSFILVTTALTMGREI SALEDCAQEQMRLRAQVRLL ETRVKQQQVKIKQLLQENEV QFLDKGDENTVIDLGSKRQY ADCSEIFNDGYKLSGFYKIK PLQSPAEFSVYCDMSDGGGW TVIQRRSDGSENFNRGWKDY ENGFGNFVQKHGEYWLGNKN LHFLTTQEDYTLKIDLADFE KNSRYAQYKNFKVGDEKNFY ELNIGEYSGTAGDSLAGNFH PEVQWWASHQRMKFSTWDR |
| Tissue Specificity | Under normal conditions, liver-specific. |
| Function | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. |
| Protein Name | Fibrinogen-Like Protein 1Hp-041HepassocinHpsHepatocyte-Derived Fibrinogen-Related Protein 1Hfrep-1Liver Fibrinogen-Related Protein 1Lfire-1 |
| Cellular Localisation | SecretedSecreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Fibrinogen-Like Protein 1 antibodyAnti-Hp-041 antibodyAnti-Hepassocin antibodyAnti-Hps antibodyAnti-Hepatocyte-Derived Fibrinogen-Related Protein 1 antibodyAnti-Hfrep-1 antibodyAnti-Liver Fibrinogen-Related Protein 1 antibodyAnti-Lfire-1 antibodyAnti-FGL1 antibodyAnti-HFREP1 antibody |
Information sourced from Uniprot.org
