| Short Description : | Mouse monoclonal anti-FGF21 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZN71 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 0.5-1.0 mg/mL |
| Purification: | Affinity Chromatography |
| Dilution Range: | IHC 1:50-1:100 |
| Formulation: | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | FGF21 |
| Gene ID: | 26291 |
| Uniprot ID: | FGF21_HUMAN |
| Immunogen: | Human recombinant protein fragment of human FGF21 (NP_061986) produced in E.coli. |
| Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
| Protein Name | Fibroblast Growth Factor 21Fgf-21 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 21 antibodyAnti-Fgf-21 antibodyAnti-FGF21 antibodyAnti-UNQ3115 antibodyAnti-PRO10196 antibody |
Information sourced from Uniprot.org
