Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Pig |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Fibroblast growth factor 19 is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:1000-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FGF19 |
Gene ID: | 9965 |
Uniprot ID: | FGF19_HUMAN |
Specificity: | This antibody detects endogenous levels of Human FGF-19 |
Immunogen: | Synthesized peptide derived from human FGF-19 |
Tissue Specificity | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
Protein Name | Fibroblast Growth Factor 19 Fgf-19 |
Database Links | Reactome: R-HSA-109704 Reactome: R-HSA-1257604 Reactome: R-HSA-1307965 Reactome: R-HSA-190322 Reactome: R-HSA-2219530 Reactome: R-HSA-5654228 Reactome: R-HSA-5654712 Reactome: R-HSA-5654719 Reactome: R-HSA-5654720 Reactome: R-HSA-5654733 Reactome: R-HSA-5673001 Reactome: R-HSA-6811558 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Fibroblast Growth Factor 19 antibody Anti-Fgf-19 antibody Anti-FGF19 antibody Anti-UNQ334 antibody Anti-PRO533 antibody |
Information sourced from Uniprot.org