| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-FYVE, RhoGEF and PH domain-containing protein 4 (291-341 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGD4 |
| Gene ID: | 121512 |
| Uniprot ID: | FGD4_HUMAN |
| Immunogen Region: | 291-341 aa |
| Specificity: | This antibody detects endogenous levels of FGD4 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human FGD4 at the amino acid range 291-341 |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4Actin Filament-Binding Protein FrabinFgd1-Related F-Actin-Binding ProteinZinc Finger Fyve Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionFilopodiumConcentrated In Filopodia And Poorly Detected At LamellipodiaBinds Along The Sides Of Actin Fibers |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 4 antibodyAnti-Actin Filament-Binding Protein Frabin antibodyAnti-Fgd1-Related F-Actin-Binding Protein antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 6 antibodyAnti-FGD4 antibodyAnti-FRABP antibodyAnti-ZFYVE6 antibody |
Information sourced from Uniprot.org