Anti-FGD1 antibody (700-800) (STJ118802)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FGD1 (700-800) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FGD1 |
| Gene ID | 2245 |
| Uniprot ID | FGD1_HUMAN |
| Immunogen Region | 700-800 |
| Immunogen Sequence | LLNSTNREDEDTPPNSPNVD LGKRAPTPIREKEVTMCMRC QEPFNSITKRRHHCKACGHV VCGKCSEFRARLVYDNNRSN RVCTDCYVALHGVPGSSPAC S |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2). |
Additional Info
| Tissue Specificity | Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver.adult heart, brain, lung, pancreas and skeletal muscle. |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 1Faciogenital Dysplasia 1 ProteinRho/Rac Guanine Nucleotide Exchange Factor Fgd1Rho/Rac GefZinc Finger Fyve Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCell ProjectionLamellipodiumRuffleCytoskeletonAssociated With Membrane Ruffles And Lamellipodia |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 1 antibodyAnti-Faciogenital Dysplasia 1 Protein antibodyAnti-Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 antibodyAnti-Rho/Rac Gef antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 3 antibodyAnti-FGD1 antibodyAnti-FGDY antibodyAnti-ZFYVE3 antibody |
Information sourced from Uniprot.org