| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FYVE, RhoGEF and PH domain-containing protein 1 (508-558 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FGD1 |
| Gene ID: |
2245 |
| Uniprot ID: |
FGD1_HUMAN |
| Immunogen Region: |
508-558 aa |
| Specificity: |
This antibody detects endogenous levels of FGD1 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human FGD1 at the amino acid range 508-558 |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 1Faciogenital Dysplasia 1 ProteinRho/Rac Guanine Nucleotide Exchange Factor Fgd1Rho/Rac GefZinc Finger Fyve Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCell ProjectionLamellipodiumRuffleCytoskeletonAssociated With Membrane Ruffles And Lamellipodia |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 1 antibodyAnti-Faciogenital Dysplasia 1 Protein antibodyAnti-Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 antibodyAnti-Rho/Rac Gef antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 3 antibodyAnti-FGD1 antibodyAnti-FGDY antibodyAnti-ZFYVE3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
