Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FYVE, RhoGEF and PH domain-containing protein 1 (508-558 aa) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FGD1 |
Gene ID: | 2245 |
Uniprot ID: | FGD1_HUMAN |
Immunogen Region: | 508-558 aa |
Specificity: | This antibody detects endogenous levels of FGD1 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human FGD1 at the amino acid range 508-558 |
Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 1 Faciogenital Dysplasia 1 Protein Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 Rho/Rac Gef Zinc Finger Fyve Domain-Containing Protein 3 |
Database Links | Reactome: R-HSA-193648 Reactome: R-HSA-416482 Reactome: R-HSA-9013148 |
Cellular Localisation | Cytoplasm Cell Projection Lamellipodium Ruffle Cytoskeleton Associated With Membrane Ruffles And Lamellipodia |
Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 1 antibody Anti-Faciogenital Dysplasia 1 Protein antibody Anti-Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 antibody Anti-Rho/Rac Gef antibody Anti-Zinc Finger Fyve Domain-Containing Protein 3 antibody Anti-FGD1 antibody Anti-FGDY antibody Anti-ZFYVE3 antibody |
Information sourced from Uniprot.org