Western blot analysis of extracts of various cell lines, using FPS/FDPS antibody (STJ11104093) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-FDPS antibody (320-419) [S4093RM] (STJ11104093)

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STJ11104093
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S4093RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FDPS
Gene ID: 2224
Uniprot ID: FPPS_HUMAN
Immunogen Region: 320-419
Specificity: A synthetic peptide corresponding to a sequence within amino acids 320-419 of human FPS/FDPS (P14324).
Immunogen Sequence: VTGKIGTDIQDNKCSWLVVQ CLQRATPEQYQILKENYGQK EAEKVARVKALYEELDLPAV FLQYEEDSYSHIMALIEQYA APLPPAVFLGLARKIYKRRK
Function Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Protein Name Farnesyl Pyrophosphate Synthase
Fpp Synthase
Fps
(2e -6e-Farnesyl Diphosphate Synthase
Dimethylallyltranstransferase
Farnesyl Diphosphate Synthase
Geranyltranstransferase
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-2426168
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Farnesyl Pyrophosphate Synthase antibody
Anti-Fpp Synthase antibody
Anti-Fps antibody
Anti-(2e -6e-Farnesyl Diphosphate Synthase antibody
Anti-Dimethylallyltranstransferase antibody
Anti-Farnesyl Diphosphate Synthase antibody
Anti-Geranyltranstransferase antibody
Anti-FDPS antibody
Anti-FPS antibody
Anti-KIAA1293 antibody

Information sourced from Uniprot.org

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