| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Squalene synthase (11-61 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FDFT1 |
| Gene ID: |
2222 |
| Uniprot ID: |
FDFT_HUMAN |
| Immunogen Region: |
11-61 aa |
| Specificity: |
This antibody detects endogenous levels of FDFT at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human FDFT at the amino acid range 11-61 |
| Function | Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. |
| Protein Name | Squalene SynthaseSqsSsFpp -Fpp FarnesyltransferaseFarnesyl-Diphosphate FarnesyltransferaseFarnesyl-Diphosphate Farnesyltransferase 1 |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-1989781Reactome: R-HSA-2426168 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Squalene Synthase antibodyAnti-Sqs antibodyAnti-Ss antibodyAnti-Fpp -Fpp Farnesyltransferase antibodyAnti-Farnesyl-Diphosphate Farnesyltransferase antibodyAnti-Farnesyl-Diphosphate Farnesyltransferase 1 antibodyAnti-FDFT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
