| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-High affinity immunoglobulin gamma Fc receptor I (230-280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:500-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCGR1A |
| Gene ID: | 2209 |
| Uniprot ID: | FCGR1_HUMAN |
| Immunogen Region: | 230-280 aa |
| Specificity: | The antibody detects endogenous CD64 |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 230-280 |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Antibody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I antibodyAnti-Igg Fc Receptor I antibodyAnti-Fc-Gamma Ri antibodyAnti-Fcri antibodyAnti-Fc-Gamma Ria antibodyAnti-Fcgammaria antibodyAnti-Cd Antigen Cd64 antibodyAnti-FCGR1A antibodyAnti-FCG1 antibodyAnti-FCGR1 antibodyAnti-IGFR1 antibody |
Information sourced from Uniprot.org
