Host: |
Rabbit |
Applications: |
IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-FBXO32 (206-355) is suitable for use in Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FBXO32 |
Gene ID: |
114907 |
Uniprot ID: |
FBX32_HUMAN |
Immunogen Region: |
206-355 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32 (NP_478136.1). |
Immunogen Sequence: |
WQQQLNNIQITRPAFKGLTF TDLPLCLQLNIMQRLSDGRD LVSLGQAAPDLHVLSEDRLL WKKLCQYHFSERQIRKRLIL SDKGQLDWKKMYFKLVRCYP RKEQYGDTLQLCKHCHILSW KGTDHPCTANNPESCSVSLS PQDFINLFKF |
Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
Protein Name | F-Box Only Protein 32Atrogin-1Muscle Atrophy F-Box ProteinMafbx |
Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-9615017Reactome: R-HSA-983168 |
Cellular Localisation | CytoplasmNucleusShuttles Between Cytoplasm And The Nucleus |
Alternative Antibody Names | Anti-F-Box Only Protein 32 antibodyAnti-Atrogin-1 antibodyAnti-Muscle Atrophy F-Box Protein antibodyAnti-Mafbx antibodyAnti-FBXO32 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance