| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Fructose-1, 6-bisphosphatase 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FBP1 |
| Gene ID: |
2203 |
| Uniprot ID: |
F16P1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of FBP1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human FBP1 |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity.increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| Protein Name | Fructose-1 -6-Bisphosphatase 1Fbpase 1D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1Liver Fbpase |
| Database Links | Reactome: R-HSA-70263 |
| Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase 1 antibodyAnti-Fbpase 1 antibodyAnti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 antibodyAnti-Liver Fbpase antibodyAnti-FBP1 antibodyAnti-FBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
