Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4ยฐC overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-FBN3 antibody (1311-1361 aa) (STJ196573)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human FBN3 at the amino acid range 1311-1361
STJ196573
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General Information

Short DescriptionRabbit polyclonal anti-Fibrillin-3 (1311-1361 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/IF
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeIHC-P 1:50-200
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolFBN3
Gene ID84467
Uniprot IDFBN3_HUMAN
ImmunogenSynthesized peptide derived from the human FBN3 at the amino acid range 1311-1361
Immunogen Region1311-1361 aa
SpecificityThis antibody detects endogenous levels of FBN3 at Human

Additional Info

Post Translational Modifications Probably forms intermolecular disulfide bonds either with other FBN3 molecules or with other components of the microfibrils.
Function Fibrillin-3: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support.
Protein Name Fibrillin-3 Cleaved Into - Fibrillin-3 C-Terminal Peptide
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Fibrillin-3 Cleaved Into - Fibrillin-3 C-Terminal Peptide antibody
Anti-FBN3 antibody
Anti-KIAA1776 antibody

Information sourced from Uniprot.org

Citations

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