| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Fibrillin-3 (1311-1361 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBN3 |
| Gene ID: | 84467 |
| Uniprot ID: | FBN3_HUMAN |
| Immunogen Region: | 1311-1361 aa |
| Specificity: | This antibody detects endogenous levels of FBN3 at Human |
| Immunogen: | Synthesized peptide derived from the human FBN3 at the amino acid range 1311-1361 |
| Post Translational Modifications | Probably forms intermolecular disulfide bonds either with other FBN3 molecules or with other components of the microfibrils. |
| Function | Fibrillin-3: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support. |
| Protein Name | Fibrillin-3 Cleaved Into - Fibrillin-3 C-Terminal Peptide |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-1566948Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Fibrillin-3 Cleaved Into - Fibrillin-3 C-Terminal Peptide antibodyAnti-FBN3 antibodyAnti-KIAA1776 antibody |
Information sourced from Uniprot.org
