| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAT4 |
| Gene ID: | 79633 |
| Uniprot ID: | FAT4_HUMAN |
| Immunogen Region: | 4900-4981 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 4900-4981 of human FAT4 (NP_078858.4). |
| Immunogen Sequence: | GGPVGTQAAAPGTADNTLPM KLGQQAGTFNWDNLLNWGPG FGHYVDVFKDLASLPEKAAA NEEGKAGTTKPVPKDGEAEQ YV |
| Tissue Specificity | Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation. |
| Protein Name | Protocadherin Fat 4Hfat4Cadherin Family Member 14Fat Tumor Suppressor Homolog 4Fat-Like Cadherin Protein Fat-J |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIn The KidneyLocalizes To Primary Cilia |
| Alternative Antibody Names | Anti-Protocadherin Fat 4 antibodyAnti-Hfat4 antibodyAnti-Cadherin Family Member 14 antibodyAnti-Fat Tumor Suppressor Homolog 4 antibodyAnti-Fat-Like Cadherin Protein Fat-J antibodyAnti-FAT4 antibodyAnti-CDHF14 antibodyAnti-FATJ antibodyAnti-Nbla00548 antibody |
Information sourced from Uniprot.org