Anti-FAT1 antibody (2700-2900 aa) (STJ11106135)

SKU:
STJ11106135
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: FAT1
Gene ID: 2195
Uniprot ID: FAT1_HUMAN
Immunogen Region: 2700-2900 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 2700-2900 of human FAT1 (NP_005236.2).
Immunogen Sequence: LPKFSEPFYTFTVSEDVPIG TEIDLIRAEHSGTVLYSLVK GNTPESNRDESFVIDRQSGR LKLEKSLDHETTKWYQFSIL ARCTQDDHEMVASVDVSIQV KDANDNSPVFESSPYEAFIV ENLPGGSRVIQIRASDADSG TNGQVMYSLDQSQSVEVIES FAINMETGWITTLKELDHEK RDNYQIKVVASDHGEKIQLS S
Tissue Specificity Expressed in many epithelial and some endothelial and smooth muscle cells.
Post Translational Modifications Undergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus.
Function Protocadherin Fat 1: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
Protein Name Protocadherin Fat 1
Cadherin Family Member 7
Cadherin-Related Tumor Suppressor Homolog
Protein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form
Cellular Localisation Protocadherin Fat 1: Cell Membrane
Single-Pass Type I Membrane Protein
Protocadherin Fat 1
Nuclear Form: Nucleus
Alternative Antibody Names Anti-Protocadherin Fat 1 antibody
Anti-Cadherin Family Member 7 antibody
Anti-Cadherin-Related Tumor Suppressor Homolog antibody
Anti-Protein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form antibody
Anti-FAT1 antibody
Anti-CDHF7 antibody
Anti-FAT antibody

Information sourced from Uniprot.org

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