Anti-FAT1 antibody (1140-1220 aa) (STJ190301)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1140-1220
General Information
| Short Description | Rabbit polyclonal anti-Protocadherin Fat 1 (1140-1220 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-300IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAT1 |
| Gene ID | 2195 |
| Uniprot ID | FAT1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1140-1220 |
| Immunogen Region | 1140-1220 aa |
| Specificity | FAT1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Undergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus. |
| Function | Protocadherin Fat 1: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. |
| Protein Name | Protocadherin Fat 1Cadherin Family Member 7Cadherin-Related Tumor Suppressor HomologProtein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form |
| Database Links | |
| Cellular Localisation | Protocadherin Fat 1: Cell MembraneSingle-Pass Type I Membrane ProteinProtocadherin Fat 1Nuclear Form: Nucleus |
| Alternative Antibody Names | Anti-Protocadherin Fat 1 antibodyAnti-Cadherin Family Member 7 antibodyAnti-Cadherin-Related Tumor Suppressor Homolog antibodyAnti-Protein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form antibodyAnti-FAT1 antibodyAnti-CDHF7 antibodyAnti-FAT antibody |
Information sourced from Uniprot.org