• Immunofluorescence analysis of NIH/3T3 cells using FANCC antibody (STJ23623) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of paraffin-embedded Rat testis using FANCC antibody (STJ23623) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded Mouse brain using FANCC antibody (STJ23623) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human liver cancer using FANCC antibody (STJ23623) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using FANCC antibody (STJ23623) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-FANCC antibody (340-558) (STJ23623)

SKU:
STJ23623

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FANCC (340-558) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FANCC
Gene ID: 2176
Uniprot ID: FANCC_HUMAN
Immunogen Region: 340-558
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 340-558 of human FANCC (NP_000127.2).
Immunogen Sequence: YFPYTSPSLAMVLLQDPQDI PRGHWLQTLKHISELLREAV EDQTHGSCGGPFESWFLFIH FGGWAEMVAEQLLMSAAEPP TALLWLLAFYYGPRDGRQQR AQTMVQVKAVLGHLLAMSRS SSLSAQDLQTVAGQGTDTDL RAPAQQLIRHLLLNFLLWAP GGHTIAWDVITLMAHTAEIT HEIIGFLDQTLYRWNRLGIE SPRSEKLARELLKELRTQV
Tissue Specificity Ubiquitous.
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
Protein Name Fanconi Anemia Group C Protein
Protein Facc
Database Links Reactome: R-HSA-6783310
Reactome: R-HSA-6796648
Cellular Localisation Nucleus
Cytoplasm
The Major Form Is Nuclear
The Minor Form Is Cytoplasmic
Alternative Antibody Names Anti-Fanconi Anemia Group C Protein antibody
Anti-Protein Facc antibody
Anti-FANCC antibody
Anti-FAC antibody
Anti-FACC antibody

Information sourced from Uniprot.org

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