| Host: | Rabbit |
| Applications: | WB/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-FANCA for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R07-1T5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IP 1:40 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | FANCA |
| Gene ID: | 2175 |
| Uniprot ID: | FANCA_HUMAN |
| Immunogen: | A synthesized peptide derived from human FANCA |
| Post Translational Modifications | Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H. |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
| Protein Name | Fanconi Anemia Group A ProteinProtein Faca |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-9833482 |
| Cellular Localisation | NucleusCytoplasmThe Major Form Is NuclearThe Minor Form Is Cytoplasmic |
| Alternative Antibody Names | Anti-Fanconi Anemia Group A Protein antibodyAnti-Protein Faca antibodyAnti-FANCA antibodyAnti-FAA antibodyAnti-FACA antibodyAnti-FANCH antibody |
Information sourced from Uniprot.org
