Anti-FANCA antibody [R07-1T5] (STJA0037104)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human FANCA
STJA0037104
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General Information

Short DescriptionRabbit monoclonal anti-FANCA for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IP
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR07-1T5
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
IP 1:40
FormulationRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolFANCA
Gene ID2175
Uniprot IDFANCA_HUMAN
ImmunogenA synthesized peptide derived from human FANCA

Additional Info

Post Translational Modifications Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H.
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Protein Name Fanconi Anemia Group A Protein
Protein Faca
Database Links Reactome: R-HSA-6783310
Reactome: R-HSA-9833482
Cellular Localisation Nucleus
Cytoplasm
The Major Form Is Nuclear
The Minor Form Is Cytoplasmic
Alternative Antibody Names Anti-Fanconi Anemia Group A Protein antibody
Anti-Protein Faca antibody
Anti-FANCA antibody
Anti-FAA antibody
Anti-FACA antibody
Anti-FANCH antibody

Information sourced from Uniprot.org

Citations

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