| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FAM3B (30-235) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAM3B |
| Gene ID: |
54097 |
| Uniprot ID: |
FAM3B_HUMAN |
| Immunogen Region: |
30-235 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3). |
| Immunogen Sequence: |
ELIPDAPLSSAAYSIRSIGE RPVLKAPVPKRQKCDHWTPC PSDTYAYRLLSGGGRSKYAK ICFEDNLLMGEQLGNVARGI NIAIVNYVTGNVTATRCFDM YEGDNSGPMTKFIQSAAPKS LLFMVTYDDGSTRLNNDAKN AIEALGSKEIRNMKFRSSWV FIAAKGLELPSEIQREKINH SDAKNNRYSGWPAEIQIEGC IPKERS |
| Tissue Specificity | Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis. |
| Post Translational Modifications | 2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46. O-glycosylated. |
| Function | Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. |
| Protein Name | Protein Fam3bCytokine-Like Protein 2-21Pancreatic-Derived FactorPander |
| Cellular Localisation | SecretedPresent In Insulin Secretory Granules And Likely Cosecreted With InsulinLocalized In Discrete Vesicular And Perinuclear Structure |
| Alternative Antibody Names | Anti-Protein Fam3b antibodyAnti-Cytokine-Like Protein 2-21 antibodyAnti-Pancreatic-Derived Factor antibodyAnti-Pander antibodyAnti-FAM3B antibodyAnti-C21orf11 antibodyAnti-C21orf76 antibodyAnti-PRED44 antibodyAnti-UNQ320 antibodyAnti-PRO365 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
