Anti-FAM213A antibody (STJA0004722)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human FAM213A
General Information
| Short Description | Rabbit polyclonal anti-Peroxiredoxin-Like 2a for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.02 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PRXL2A |
| Gene ID | 84293 |
| Uniprot ID | PXL2A_HUMAN |
| Immunogen | Synthetic peptide of human FAM213A |
Additional Info
| Tissue Specificity | Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs). |
| Function | Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway. |
| Protein Name | Peroxiredoxin-Like 2aPeroxiredoxin-Like 2 Activated In M-Csf Stimulated MonocytesProtein PammRedox-Regulatory Protein Fam213a |
| Database Links | |
| Cellular Localisation | CytoplasmSecretedSecreted From Mature Adipocytes But Not From Preadipocytes |
| Alternative Antibody Names | Anti-Peroxiredoxin-Like 2a antibodyAnti-Peroxiredoxin-Like 2 Activated In M-Csf Stimulated Monocytes antibodyAnti-Protein Pamm antibodyAnti-Redox-Regulatory Protein Fam213a antibodyAnti-PRXL2A antibodyAnti-C10orf58 antibodyAnti-FAM213A antibodyAnti-PAMM antibodyAnti-PRO2290 antibodyAnti-PSEC0139 antibodyAnti-UNQ611 antibodyAnti-PRO1198 antibody |
Information sourced from Uniprot.org