Anti-Factor XIIIa antibody [ZM84] (STJ180323)

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STJ180323
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Short Description :Mouse monoclonal Factor XIIIa antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :ZM84
Isotype:IgG2ak
Conjugation:Unconjugated
Purification:Affinity purified
Dilution Range:1:100‐200
Formulation:Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage Instruction:Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol:F13A1
Gene ID:2162
Uniprot ID:F13A_HUMAN
Immunogen:Recombinant fragment of human Factor XIIIa protein
Specificity:Positive control: Capillary hemangioma, dermatofibroma, and placenta
Post Translational Modifications The activation peptide is released by thrombin.
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Protein Name Coagulation Factor Xiii A Chain
Coagulation Factor Xiiia
Protein-Glutamine Gamma-Glutamyltransferase A Chain
Transglutaminase A Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140875
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Secreted
Secreted Into The Blood Plasma
Cytoplasmic In Most Tissues
But Also Secreted In The Blood Plasma
Alternative Antibody Names Anti-Coagulation Factor Xiii A Chain antibody
Anti-Coagulation Factor Xiiia antibody
Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody
Anti-Transglutaminase A Chain antibody
Anti-F13A1 antibody
Anti-F13A antibody

Information sourced from Uniprot.org